Cerebrospinal fluid Aβ40 improves the interpretation of Aβ42 concentration for diagnosing Alzheimer’s disease.

The combination of decreased amyloid β42 (Aβ42) and increased total tau proteins (T-Tau) and phosphorylated tau (P-Tau) in cerebrospinal fluid (CSF) has recently been considered as a biological diagnostic criterion of Alzheimer’s disease (AD). Previous studies showed significant heterogeneity in CSF...

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Bibliographic Details
Main Authors: Aline eDorey, Armand ePerret-Liaudet, Yannick eTholance, Anthony eFourier, Isabelle eQuadrio
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-11-01
Series:Frontiers in Neurology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fneur.2015.00247/full