Phosphorylation of Akt by SC79 Prevents Iron Accumulation and Ameliorates Early Brain Injury in a Model of Experimental Subarachnoid Hemorrhage

Phosphorylation of Akt by SC79 Prevents Iron Accumulation and Ameliorates Early Brain Injury in a Model of Experimental Subarachnoid Hemorrhage

Previous studies have demonstrated that activation of Akt may alleviate early brain injury (EBI) following subarachnoid hemorrhage (SAH). This study is undertaken to determine whether iron metabolism is involved in the beneficial effect of Akt activation after SAH. Therefore, we used a novel molecul...

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Bibliographic Details
Main Authors: Shuangying Hao, Chuanhui Song, Longcheng Shang, Jiang Yu, Tong Qiao, Kuanyu Li
Format: Article
Language:English
Published: MDPI AG 2016-03-01
Series:Molecules
Subjects:
subarachnoid hemorrhage
SC79
Akt phosphorylation
oxidative stress
iron homeostasis
Fe-S cluster biogenesis
Online Access:http://www.mdpi.com/1420-3049/21/3/325

Internet

http://www.mdpi.com/1420-3049/21/3/325

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