TRADD Mediates RIPK1-Independent Necroptosis Induced by Tumor Necrosis Factor

As a programmed necrotic cell death, necroptosis has the intrinsic initiators, including receptor-interacting serine/threonine-protein kinase 1 (RIPK1), RIPK3 and mixed-lineage kinase domain-like protein (MLKL), which combine to form necroptotic signaling pathway and mediate necroptosis induced by v...

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Bibliographic Details
Main Authors: Lili Wang, Xixi Chang, Jinli Feng, Jiyun Yu, Guozhu Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2019.00393/full