Preparative Scale Resolution of Enantiomers Enables Accelerated Drug Discovery and Development

Preparative Scale Resolution of Enantiomers Enables Accelerated Drug Discovery and Development

The provision of pure enantiomers is of increasing importance not only for the pharmaceutical industry but also for agro-chemistry and biotechnology. In drug discovery and development, the enantiomers of a chiral drug depict unique chemical and pharmacological behaviors in a chiral environment, such...

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Bibliographic Details
Main Authors: Hanna Leek, Shalini Andersson
Format: Article
Language:English
Published: MDPI AG 2017-01-01
Series:Molecules
Subjects:
chiral resolution
chiral stationary phases
preparative chromatography
supercritical fluidchromatography
racemization
active pharmaceutical ingredient
drug discovery
drug development
Online Access:http://www.mdpi.com/1420-3049/22/1/158

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http://www.mdpi.com/1420-3049/22/1/158

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