The effect of 5α-oleandrin on keloid fibroblast activities

The effect of 5α-oleandrin on keloid fibroblast activities

Abstract Background Keloids develop due to hyperactivity of keloid fibroblast (KF) in proliferation, migration, and collagen deposition along with low rates of collagen degradation. These are a result of the Wnt/β catenin signaling pathways under stimulation of TGF-β. 5α-oleandrin can suppress Wnt-t...

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Bibliographic Details
Main Authors: Ishandono Dachlan, Yohanes Widodo Wirohadidjojo, Mae Sri Hartati Wahyuningsih, Teguh Aryandono, Hardyanto Soebono, Dwiki Afandy
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Proceedings
Subjects:
Cell proliferation
Fibroblasts
Keloid
Mitomycin
5α-oleandrin
Online Access:https://doi.org/10.1186/s12919-019-0177-6

Internet

https://doi.org/10.1186/s12919-019-0177-6

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