Oncolytic adenovirus mediated Survivin knockdown by RNA interference suppresses human colorectal carcinoma growth in vitro and in vivo

<p>Abstract</p> <p>Background</p> <p>Colorectal cancer is a one of the most common alimentary malignancies. Survivin has been proved by many studies to be an ideal target for cancer gene therapy because of its strong anti-apoptotic effect. The reduction of Survivin expr...

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Bibliographic Details
Main Authors: Wang Chun-Yi, Shen Wei, Wang Xue-Hu, Fu Zhong-Xue
Format: Article
Language:English
Published: BMC 2009-06-01
Series:Journal of Experimental & Clinical Cancer Research
Online Access:http://www.jeccr.com/content/28/1/81