Monoacylglycerol lipase (MAGL) inhibition attenuates acute lung injury in mice.

Monoacylglycerol lipase (MAGL) inhibition attenuates acute lung injury in mice.

Endocannabinoid signaling is terminated by enzymatic hydrolysis, a process that, for 2-Arachidonoylglycerol (2-AG), is mediated by monoacylglycerol lipase (MAGL). The piperidine carbamate, 4-nitrophenyl- 4-(dibenzo[d] [1,3]dioxol-5-yl (hydroxy) methyl) piperidine- 1-carboxylate (JZL184), is a drug t...

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Bibliographic Details
Main Authors: Carolina Costola-de-Souza, Alison Ribeiro, Viviane Ferraz-de-Paula, Atilio Sersun Calefi, Thiago Pinheiro Arrais Aloia, João Antonio Gimenes-Júnior, Vinicius Izidio de Almeida, Milena Lobão Pinheiro, João Palermo-Neto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3808422?pdf=render

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http://europepmc.org/articles/PMC3808422?pdf=render

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