Phosphatidylserine improves axonal transport by inhibition of HDAC and has potential in treatment of neurodegenerative diseases

Phosphatidylserine improves axonal transport by inhibition of HDAC and has potential in treatment of neurodegenerative diseases

Familial dysautonomia (FD) is a rare children neurodegenerative disease caused due to a point mutation in the IKBKAP gene that results in decreased IKK complex-associated protein (IKAP) protein production. The disease affects mostly the dorsal root ganglion (DRG) and the sympathetic ganglion. Recent...

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Bibliographic Details
Main Authors: Shiran Naftelberg, Gil Ast, Eran Perlson
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Neural Regeneration Research
Subjects:
axonal transport; neurodegeneration; microtubule; familial dysautonomia; phosphatidylserine; HDAC6
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2017;volume=12;issue=4;spage=534;epage=537;aulast=Naftelberg

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2017;volume=12;issue=4;spage=534;epage=537;aulast=Naftelberg

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