In vitro effects of different 8-methoxypsoralen treatment protocols for extracorporeal photopheresis on mononuclear cells

Extracorporeal photopheresis (ECP) is an important second-line therapy for graft- versus -host disease. A central therapeutic mechanism is the induction of immune tolerance through apoptosis in patient’s leukocytes, caused by ex vivo incubation with 8-methoxypsoralen (8-MOP) and subsequent UVA irrad...

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Bibliographic Details
Main Authors: Holger Budde, Ulrike Berntsch, Joachim Riggert, Tobias J. Legler
Format: Article
Language:English
Published: Termedia Publishing House 2017-05-01
Series:Central European Journal of Immunology
Subjects:
Online Access:https://www.termedia.pl/-In-vitro-effects-of-different-8-methoxypsoralen-treatment-protocols-for-extracorporeal-photopheresis-on-mononuclear-cells,10,29840,1,1.html