Palmitoylation and membrane cholesterol stabilize μ-opioid receptor homodimerization and G protein coupling

Palmitoylation and membrane cholesterol stabilize μ-opioid receptor homodimerization and G protein coupling

<p>Abstract</p> <p>Background</p> <p>A cholesterol-palmitoyl interaction has been reported to occur in the dimeric interface of the β<sub>2</sub>-adrenergic receptor crystal structure. We sought to investigate whether a similar phenomenon could be observed w...

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Bibliographic Details
Main Authors: Zheng Hui, Pearsall Elizabeth A, Hurst Dow P, Zhang Yuhan, Chu Ji, Zhou Yali, Reggio Patricia H, Loh Horace H, Law Ping-Yee
Format: Article
Language:English
Published: BMC 2012-03-01
Series:BMC Cell Biology
Subjects:
Palmitoylation
Cholesterol
Homodimerization
G protein coupling
Online Access:http://www.biomedcentral.com/1471-2121/13/6

Internet

http://www.biomedcentral.com/1471-2121/13/6

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