Expression of Osteoarthritis Marker YKL-39 is Stimulated by Transforming Growth Factor Beta (TGF-beta) and IL-4 in Differentiating Macrophages

Expression of Osteoarthritis Marker YKL-39 is Stimulated by Transforming Growth Factor Beta (TGF-beta) and IL-4 in Differentiating Macrophages

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YKL-39 is a Glyco_18 domain containing chitinase-like protein which is currently recognized as a biomarker for the activation of chondrocytes and the progress of the osteoarthritis in human. YKL-39 was identified as an abundantly secreted protein in primary culture of human articular chondrocytes. T...

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Bibliographic Details
Main Authors: Julia Kzhyshkowska, Sergij Goerdt, LiMing Gooi, Christina Schmuttermaier, Srinivas Mamidi, Alexei Gratchev
Format: Article
Language:English
Published: SAGE Publishing 2008-01-01
Series:Biomarker Insights
Subjects:
osteoarthritis
chitinase
YKL-39
macrophage
TGF-beta
IL-4
Online Access:http://la-press.com/article.php?article_id=560

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http://la-press.com/article.php?article_id=560

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