A Sesquiterpenoid from Farfarae Flos Induces Apoptosis of MDA-MB-231 Human Breast Cancer Cells through Inhibition of JAK–STAT3 Signaling

A Sesquiterpenoid from Farfarae Flos Induces Apoptosis of MDA-MB-231 Human Breast Cancer Cells through Inhibition of JAK–STAT3 Signaling

Triple-negative breast cancers (TNBCs) are hard-to-treat breast tumors with poor prognosis, which need to be treated by chemotherapy. Signal transducer and activator of transcription 3 (STAT3) is a transcription factor involved in proliferation, metastasis, and invasion of cancer cells. Therefore, r...

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Bibliographic Details
Main Authors: Hyeri Jang, Hyejin Ko, Kwangho Song, Yeong Shik Kim
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Biomolecules
Subjects:
Farfarae Flos
sesquiterpenoid
anticancer
STAT3
triple-negative breast cancer (TNBC)
MDA-MB-231 cells
Online Access:https://www.mdpi.com/2218-273X/9/7/278

Internet

https://www.mdpi.com/2218-273X/9/7/278

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