Inhibition of GSK 3β activity is associated with excessive EZH2 expression and enhanced tumour invasion in nasopharyngeal carcinoma.

Inhibition of GSK 3β activity is associated with excessive EZH2 expression and enhanced tumour invasion in nasopharyngeal carcinoma.

BACKGROUND:Enhancer of zeste homolog 2 (EZH2) has been shown to contribute to tumour development and/or progression. However, the signalling pathway underlying the regulation of EZH2 in nasopharyngeal carcinoma (NPC) remains unclear. Since EZH2 contains the putative Glycogen synthase kinase 3 beta (...

Full description

Bibliographic Details
Main Authors: Renqiang Ma, Yi Wei, Xiaoming Huang, Ran Fu, Xi Luo, Xiaolin Zhu, Wenbin Lei, Jugao Fang, Huabin Li, Weiping Wen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3715493?pdf=render

Similar Items

Similar Items