Inhibition of GSK 3β activity is associated with excessive EZH2 expression and enhanced tumour invasion in nasopharyngeal carcinoma.

BACKGROUND:Enhancer of zeste homolog 2 (EZH2) has been shown to contribute to tumour development and/or progression. However, the signalling pathway underlying the regulation of EZH2 in nasopharyngeal carcinoma (NPC) remains unclear. Since EZH2 contains the putative Glycogen synthase kinase 3 beta (...

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Bibliographic Details
Main Authors: Renqiang Ma, Yi Wei, Xiaoming Huang, Ran Fu, Xi Luo, Xiaolin Zhu, Wenbin Lei, Jugao Fang, Huabin Li, Weiping Wen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3715493?pdf=render