Patient-specific effects of soluble factors from Staphylococcus aureus and Staphylococcus epidermidis biofilms on osteogenic differentiation of primary human osteoblasts

Abstract Due to the frequency of biofilm-forming Staphylococcus aureus and Staphylococcus epidermidis in orthopedics, it is crucial to understand the interaction between the soluble factors produced by prokaryotes and their effects on eukaryotes. Our knowledge concerning the effect of soluble biofil...

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Bibliographic Details
Main Authors: Jutta Tübel, Elisabeth Maier, Magdalena Jegen, Carmen Marthen, Andreas Obermeier, Alexander T. Haug, Jochen Schneider, Rainer Burgkart
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-96719-4