Avoiding dangerous missense: thermophiles display especially low mutation rates.
Rates of spontaneous mutation have been estimated under optimal growth conditions for a variety of DNA-based microbes, including viruses, bacteria, and eukaryotes. When expressed as genomic mutation rates, most of the values were in the vicinity of 0.003-0.004 with a range of less than two-fold. Bec...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2009-06-01
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| Series: | PLoS Genetics |
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19543367/?tool=EBI |