Neuroinflammation as a target for treatment of stroke using mesenchymal stem cells and extracellular vesicles
Abstract Ischemic stroke is the third cause of death in the developed countries and the main reason of severe disability. Brain ischemia leads to the production of damage-associated molecular patterns (DAMPs) by neurons and glial cells which results in astrocyte and microglia activation, pro-inflamm...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-09-01
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Series: | Journal of Neuroinflammation |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12974-019-1571-8 |