Neuroinflammation as a target for treatment of stroke using mesenchymal stem cells and extracellular vesicles

Abstract Ischemic stroke is the third cause of death in the developed countries and the main reason of severe disability. Brain ischemia leads to the production of damage-associated molecular patterns (DAMPs) by neurons and glial cells which results in astrocyte and microglia activation, pro-inflamm...

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Bibliographic Details
Main Authors: Sylwia Dabrowska, Anna Andrzejewska, Barbara Lukomska, Miroslaw Janowski
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Journal of Neuroinflammation
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12974-019-1571-8