Keratinocyte Growth Factor 2 Ameliorates UVB-Induced Skin Damage via Activating the AhR/Nrf2 Signaling Pathway

Keratinocyte Growth Factor 2 Ameliorates UVB-Induced Skin Damage via Activating the AhR/Nrf2 Signaling Pathway

Objective: Exposure to ultraviolet B (UVB) can cause skin damage through oxidative stress, DNA damage, and apoptosis. Keratinocyte growth factor (KGF) has been shown to reduce the content of intracellular reactive oxygen species (ROS) following UVB exposure, a role that is crucial for the efficient...

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Bibliographic Details
Main Authors: Shuang Gao, Keke Guo, Yu Chen, Jungang Zhao, Rongrong Jing, Lusheng Wang, Xuenan Li, Zhenlin Hu, Nuo Xu, Xiaokun Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Pharmacology
Subjects:
keratinocyte growth factor 2
ultraviolet B
photoprotective
aryl hydrocarbon receptor
Nrf2
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.655281/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.655281/full

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