Smac mimetics and TRAIL cooperate to induce MLKL-dependent necroptosis in Burkitt's lymphoma cell lines

Burkitt's lymphoma (BL) is a highly aggressive form of B-cell non-Hodgkin's lymphoma. The clinical outcome in children with BL has improved over the last years but the prognosis for adults is still poor, highlighting the need for novel treatment strategies. Here, we report that the combina...

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Bibliographic Details
Main Authors: Annkathrin Koch, Birte Jeiler, Jens Roedig, Sjoerd J.L. van Wijk, Nadezda Dolgikh, Simone Fulda
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558621000130