Population modeling of tumor growth curves and the reduced Gompertz model improve prediction of the age of experimental tumors.

Tumor growth curves are classically modeled by means of ordinary differential equations. In analyzing the Gompertz model several studies have reported a striking correlation between the two parameters of the model, which could be used to reduce the dimensionality and improve predictive power. We ana...

Full description

Bibliographic Details
Main Authors: Cristina Vaghi, Anne Rodallec, Raphaëlle Fanciullino, Joseph Ciccolini, Jonathan P Mochel, Michalis Mastri, Clair Poignard, John M L Ebos, Sébastien Benzekry
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-02-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1007178