High Glucose Downregulates Connexin 43 Expression and Its Gap Junction and Hemichannel Function in Osteocyte-like MLO-Y4 Cells Through Activation of the p38MAPK/ERK Signal Pathway

Lei Yang,1 Guangping Zhou,2 Mingyang Li,1 Yan Li,1 Liqing Yang,1 Qin Fu,1 Ye Tian1 1Orthopedics Department, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, People’s Republic of China; 2Orthopedics Department, Shenyang Orthopedics Hospital, Shenyang, Liaoning Pr...

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Bibliographic Details
Main Authors: Yang L, Zhou G, Li M, Li Y, Fu Q, Tian Y
Format: Article
Language:English
Published: Dove Medical Press 2020-02-01
Series:Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy
Subjects:
Online Access:https://www.dovepress.com/high-glucose-downregulates-connexin-43-expression-and-its-gap-junction-peer-reviewed-article-DMSO