PD-1/PD-L1 regulates Treg differentiation in pregnancy-induced hypertension

PD-1/PD-L1 regulates Treg differentiation in pregnancy-induced hypertension

Pregnancy-induced hypertension (PIH) causes significant maternal and fetal morbidity and mortality. A decreased number of regulatory T (Treg) cells is associated with the pathogenesis of PIH. The programmed cell death-1 (PD-1)/PD-ligand 1 (PD-L1) pathway is critical to normal pregnancy (NP) by promo...

Full description

Bibliographic Details
Main Authors: Lai Jiang, Chaoliang Tang, Yanping Gong, Yujie Liu, Jie Rao, Suyu Chen, Wanjun Qu, Dabao Wu, Lei Lei, Ling Chen
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2018-05-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
PD-1/PD-L1
Treg
PIH
Foxp3
Differentiation
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000800605&lng=en&tlng=en

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000800605&lng=en&tlng=en

Similar Items