Perturbation of mouse retinal vascular morphogenesis by anthrax lethal toxin.

Lethal factor, the enzymatic moiety of anthrax lethal toxin (LeTx) is a protease that inactivates mitogen activated protein kinase kinases (MEK or MKK). In vitro and in vivo studies demonstrate LeTx targets endothelial cells. However, the effects of LeTx on endothelial cells are incompletely charact...

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Bibliographic Details
Main Authors: Jennifer L Bromberg-White, Elissa Boguslawski, Nicholas S Duesbery
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2737623?pdf=render