Self-consistent theory of transcriptional control in complex regulatory architectures.

Individual regulatory proteins are typically charged with the simultaneous regulation of a battery of different genes. As a result, when one of these proteins is limiting, competitive effects have a significant impact on the transcriptional response of the regulated genes. Here we present a general...

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Bibliographic Details
Main Authors: Jasper Landman, Robert C Brewster, Franz M Weinert, Rob Phillips, Willem K Kegel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5501422?pdf=render