Evaluating the discriminatory power of a dissolution assay for rosuvastatin calcium capsules: Solid-state properties and dissolution media

Evaluating the discriminatory power of a dissolution assay for rosuvastatin calcium capsules: Solid-state properties and dissolution media

We propose to evaluate the dissolution properties of rosuvastatin calcium (ROSC) capsules in different media to characterize the discriminatory power of the assay method. Dissolution assays were performed in media with different pH, and including the surfactant sodium dodecyl sulfate (SDS). Several...

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Bibliographic Details
Main Authors: Marilene Lopes Ângelo, André Luís Morais Ruela, Anna Clara Marques Ferreira, Marcus Vinicus de Faria Ramos, Cristina Martiniano Montanari, Lucélia Magalhães da Silva, Magali Benjamim de Araújo
Format: Article
Language:English
Published: Universidade de São Paulo
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Dissolution
Crystal polymorphism
Solid dosage form
X-ray powder diffractometry
Thermal analysis
Solubility
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100527&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100527&lng=en&tlng=en

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