Epigenomics of mammary gland development

Abstract Differentiation of stem cells into highly specialised cells requires gene expression changes brought about by remodelling of the chromatin architecture. During this lineage-commitment process, the majority of DNA needs to be packaged into inactive heterochromatin, allowing only a subset of...

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Bibliographic Details
Main Authors: Holly Holliday, Laura A. Baker, Simon R. Junankar, Susan J. Clark, Alexander Swarbrick
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Breast Cancer Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13058-018-1031-x