Comparative Molecular Docking of Antitrypanosomal Natural Products into Multiple Trypanosoma brucei Drug Targets

Antitrypanosomal natural products with different structural motifs previously shown to have growth inhibitory activity against Trypanosoma brucei were docked into validated drug targets of the parasite, which include trypanothione reductase, rhodesain, farnesyl diphosphate synthase, and triosephosph...

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Bibliographic Details
Main Authors: William N. Setzer, Ifedayo V. Ogungbe
Format: Article
Language:English
Published: MDPI AG 2009-04-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/14/4/1513/