Caspase 8 and maspin are downregulated in breast cancer cells due to CpG site promoter methylation

<p>Abstract</p> <p>Background</p> <p>Epigenetic changes associated with promoter DNA methylation results in silencing of several tumor suppressor genes that lead to increased risk for tumor formation and for progression of the cancer.</p> <p>Methods</p>...

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Bibliographic Details
Main Authors: Koeffler Phillip, Slamon Dennis J, Alvarez Monica, Wu Yanyuan, Vadgama Jaydutt V
Format: Article
Language:English
Published: BMC 2010-02-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/10/32