Video-Rate Bioluminescence Imaging of Degranulation of Mast Cells Attached to the Extracellular Matrix

Degranulation refers to the secretion of inflammatory mediators, such as histamine, serotonin, and proteases, that are stored within the granules of mast cells and that trigger allergic reactions. The amount of these released mediators has been measured biochemically using cell mass. To investigate...

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Bibliographic Details
Main Authors: Satoru Yokawa, Takahiro Suzuki, Ayumi Hayashi, Satoshi Inouye, Yoshikazu Inoh, Tadahide Furuno
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2018.00074/full