8-Deoxy-Rifamycin Derivatives from <i>Amycolatopsis mediterranei</i> S699 <i>ΔrifT</i> Strain

Proansamycin X, a hypothetical earliest macrocyclic precursor in the biosynthesis of rifamycin, had never been isolated and identified. According to bioinformatics analysis, it was proposed that RifT (a putative NADH-dependent dehydrogenase) may be a candidate target responsible for the dehydrogenat...

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Bibliographic Details
Main Authors: Feng Ye, Yanrong Shi, Shengliang Zhao, Zhiying Li, Haoxin Wang, Chunhua Lu, Yuemao Shen
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/10/9/1265