Phosphorylation of HIV-1 Tat by CDK2 in HIV-1 transcription

<p>Abstract</p> <p>Background</p> <p>Transcription of HIV-1 genes is activated by HIV-1 Tat protein, which induces phosphorylation of RNA polymerase II (RNAPII) C-terminal domain (CTD) by CDK9/cyclin T1. Earlier we showed that CDK2/cyclin E phosphorylates HIV-1 Tat <...

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Bibliographic Details
Main Authors: Gordeuk Victor R, Southerland William, Klase Zachary, Charles Sharroya, Jackson Angela, Jerebtsova Marina, Berro Reem, Ammosova Tatyana, Kashanchi Fatah, Nekhai Sergei
Format: Article
Language:English
Published: BMC 2006-11-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/3/1/78