Sex Differences in Remote Contextual Fear Generalization in Mice

The generalization of fear is adaptive in that it allows an animal to respond appropriately to novel threats that are not identical to previous experiences. In contrast, the overgeneralization of fear is maladaptive and is a hallmark of post-traumatic stress disorder (PTSD), a psychiatric illness th...

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Bibliographic Details
Main Authors: Arun Asok, Joud Hijazi, Lucas R. Harvey, Stylianos Kosmidis, Eric R. Kandel, Joseph B. Rayman
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnbeh.2019.00056/full