A bioluminescence reporter mouse that monitors expression of constitutively active β-catenin.

This short technical report describes the generation and characterization of a bioluminescence reporter mouse that is engineered to detect and longitudinally monitor the expression of doxycycline-induced constitutively active β-catenin. The new responder transgenic mouse contains the TetO-ΔN89β-CatT...

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Bibliographic Details
Main Authors: Maria M Szwarc, Ramakrishna Kommagani, Mary C Peavey, Lan Hai, David M Lonard, John P Lydon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5333872?pdf=render