SUV39H1-DNMT3A-mediated epigenetic regulation of Tim-3 and galectin-9 in the cervical cancer

SUV39H1-DNMT3A-mediated epigenetic regulation of Tim-3 and galectin-9 in the cervical cancer

Abstract Background Methylation of histone 3 at lysine 9 (H3K9) and DNA methylation are epigenetic marks correlated with genes silencing. The tumor microenvironment significantly influences therapeutic responses and clinical outcomes. The epigenetic-regulation mechanism of the costimulatory factors...

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Bibliographic Details
Main Authors: Li Zhang, Sijuan Tian, Minyi Zhao, Ting Yang, Shimin Quan, Qing Yang, Lihua Song, Xiaofeng Yang
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Cancer Cell International
Subjects:
Cervical cancer
SUV39H1
H3K9me3
DNMT3A
Tim-3
Galectin-9
Online Access:http://link.springer.com/article/10.1186/s12935-020-01380-y

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http://link.springer.com/article/10.1186/s12935-020-01380-y

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