Evaluation of the efficacy & biochemical mechanism of cell death induction by Piper longum extract selectively in in-vitro and in-vivo models of human cancer cells.

Evaluation of the efficacy & biochemical mechanism of cell death induction by Piper longum extract selectively in in-vitro and in-vivo models of human cancer cells.

BACKGROUND:Currently chemotherapy is limited mostly to genotoxic drugs that are associated with severe side effects due to non-selective targeting of normal tissue. Natural products play a significant role in the development of most chemotherapeutic agents, with 74.8% of all available chemotherapy b...

Full description

Bibliographic Details
Main Authors: Pamela Ovadje, Dennis Ma, Phillip Tremblay, Alessia Roma, Matthew Steckle, Jose-Antonio Guerrero, John Thor Arnason, Siyaram Pandey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4234676?pdf=render

Internet

http://europepmc.org/articles/PMC4234676?pdf=render

Similar Items