Everolimus and Malignancy after Solid Organ Transplantation: A Clinical Update

Malignancy after solid organ transplantation remains a major cause of posttransplant mortality. The mammalian target of rapamycin (mTOR) inhibitor class of immunosuppressants exerts various antioncogenic effects, and the mTOR inhibitor everolimus is licensed for the treatment of several solid cancer...

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Bibliographic Details
Main Authors: Hallvard Holdaas, Paolo De Simone, Andreas Zuckermann
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Journal of Transplantation
Online Access:http://dx.doi.org/10.1155/2016/4369574