Quantitative nuclear histomorphometric features are predictive of Oncotype DX risk categories in ductal carcinoma in situ: preliminary findings

Quantitative nuclear histomorphometric features are predictive of Oncotype DX risk categories in ductal carcinoma in situ: preliminary findings

Abstract Background Oncotype DX (ODx) is a 12-gene assay assessing the recurrence risk (high, intermediate, and low) of ductal carcinoma in situ (pre-invasive breast cancer), which guides clinicians regarding prescription of radiotherapy. However, ODx is expensive, time-consuming, and tissue-destruc...

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Bibliographic Details
Main Authors: Haojia Li, Jon Whitney, Kaustav Bera, Hannah Gilmore, Mangesh A. Thorat, Sunil Badve, Anant Madabhushi
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Breast Cancer Research
Subjects:
Ductal carcinoma in situ
Oncotype DX
Quantitative histomorphometry
Nucleus
Online Access:http://link.springer.com/article/10.1186/s13058-019-1200-6

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http://link.springer.com/article/10.1186/s13058-019-1200-6

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