Should mast cells be considered therapeutic targets in multiple sclerosis?

Should mast cells be considered therapeutic targets in multiple sclerosis?

Mast cells are immune cells of the myeloid lineage that are found throughout the body, including the central nervous system. They perform many functions associated with innate and specific immunity, angiogenesis, and vascular homeostasis. Moreover, they have been implicated in a series of pathologie...

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Bibliographic Details
Main Authors: Karen Henriette Pinke, Sofia Fernanda Gonçalves Zorzella-Pezavento, Vanessa Soares Lara, Alexandrina Sartori
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Neural Regeneration Research
Subjects:
central nervous system; degenerative disease; experimental autoimmune encephalomyelitis; immunity; immunomodulatory drugs; inflammatory disease; ketotifen fumarate; mast cells; multiple sclerosis; therapeutic target
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2020;volume=15;issue=11;spage=1995;epage=2007;aulast=Pinke

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2020;volume=15;issue=11;spage=1995;epage=2007;aulast=Pinke

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