Inhibition of JNK signaling in the Asian malaria vector Anopheles stephensi extends mosquito longevity and improves resistance to Plasmodium falciparum infection.

Inhibition of JNK signaling in the Asian malaria vector Anopheles stephensi extends mosquito longevity and improves resistance to Plasmodium falciparum infection.

Malaria is a global health concern caused by infection with Plasmodium parasites. With rising insecticide and drug resistance, there is a critical need to develop novel control strategies, including strategies to block parasite sporogony in key mosquito vector species. MAPK signaling pathways regula...

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Bibliographic Details
Main Authors: Lattha Souvannaseng, Lewis Vibul Hun, Heather Baker, John M Klyver, Bo Wang, Nazzy Pakpour, Jordan M Bridgewater, Eleonora Napoli, Cecilia Giulivi, Michael A Riehle, Shirley Luckhart
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-11-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007418

Internet

https://doi.org/10.1371/journal.ppat.1007418

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