Thrombotic Role of Blood and Endothelial Cells in Uremia through Phosphatidylserine Exposure and Microparticle Release.

The mechanisms contributing to an increased risk of thrombosis in uremia are complex and require clarification. There is scant morphological evidence of membrane-dependent binding of factor Xa (FXa) and factor Va (FVa) on endothelial cells (EC) in vitro. Our objectives were to confirm that exposed p...

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Bibliographic Details
Main Authors: Chunyan Gao, Rui Xie, Chengyuan Yu, Ruishuang Ma, Weijun Dong, Huan Meng, Yan Zhang, Yu Si, Zhuo Zhang, Valerie Novakovic, Yong Zhang, Junjie Kou, Yayan Bi, Baoxin Li, Rujuan Xie, Gary E Gilbert, Jin Zhou, Jialan Shi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4646287?pdf=render