NMDAR-Activated PP1 Dephosphorylates GluN2B to Modulate NMDAR Synaptic Content

Summary: In mature neurons, postsynaptic N-methyl-D-aspartate receptors (NMDARs) are segregated into two populations, synaptic and extrasynaptic, which differ in localization, function, and associated intracellular cascades. These two pools are connected via lateral diffusion, and receptor exchange...

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Bibliographic Details
Main Authors: Andrew M. Chiu, Jiejie Wang, Michael P. Fiske, Pavla Hubalkova, Levi Barse, John A. Gray, Antonio Sanz-Clemente
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471930796X