Calycosin attenuates doxorubicin-induced cardiotoxicity via autophagy regulation in zebrafish models

Anthracyclines are highly effective chemotherapeutics for antineoplastic treatment. However, cumulative cardiotoxicity is the main side effect with poor prognosis. No mechanism-based therapy is currently available to reverse chronic anthracycline-induced cardiotoxicity (AIC) after the deterioration...

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Bibliographic Details
Main Authors: Xiaoguang Lu, Linghui Lu, Li Gao, Yong Wang, Wei Wang
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221001608