Compound K Induces Endoplasmic Reticulum Stress and Apoptosis in Human Liver Cancer Cells by Regulating STAT3

Compound K Induces Endoplasmic Reticulum Stress and Apoptosis in Human Liver Cancer Cells by Regulating STAT3

The ginsenoside compound K (20-O-β-d-glucopyranosyl-20(S)-protopanaxadiol; CK) is an intestinal bacterial metabolite of ginseng protopanaxadiol saponin that has been reported to induce apoptosis in many cancer cells; however, the precise mechanisms of its activity in human hepatocellular ca...

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Bibliographic Details
Main Authors: Xuan Zhang, Silin Zhang, Qitong Sun, Wenjun Jiao, Yan Yan, Xuewu Zhang
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Molecules
Subjects:
ginsenoside
CK
apoptosis
STAT3
ERS
hepatoma
Online Access:http://www.mdpi.com/1420-3049/23/6/1482

Internet

http://www.mdpi.com/1420-3049/23/6/1482

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