Synthesis and Biological Evaluation of New 1,3-Thiazolidine-4-one Derivatives of 2-(4-Isobutylphenyl)propionic Acid

Synthesis and Biological Evaluation of New 1,3-Thiazolidine-4-one Derivatives of 2-(4-Isobutylphenyl)propionic Acid

New thiazolidine-4-one derivatives of 2-(4-isobutylphenyl)propionic acid (ibuprofen) have been synthesized as potential anti-inflammatory drugs. The structure of the new compounds was proved using spectral methods (FR-IR, 1H-NMR, 13C-NMR, MS). The in vitro antioxidant potential of the synthesized co...

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Bibliographic Details
Main Authors: Ioana Mirela Vasincu, Maria Apotrosoaei, Andreea-Teodora Panzariu, Frédéric Buron, Sylvain Routier, Lenuta Profire
Format: Article
Language:English
Published: MDPI AG 2014-09-01
Series:Molecules
Subjects:
ibuprofen
thiazolidine-4-one
synthesis
spectral methods
antioxidant effect
Online Access:http://www.mdpi.com/1420-3049/19/9/15005

Internet

http://www.mdpi.com/1420-3049/19/9/15005

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