Clinical transplantation using negative pressure ventilation ex situ lung perfusion with extended criteria donor lungs

Preclinical studies have shown that negative pressure ventilation ex situ lung perfusion results in less ventilator-induced lung injury compared to positive pressure ventilation of donor lungs during transplantation procedures. Here the authors perform a single-arm clinical trial with 12 participant...

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Bibliographic Details
Main Authors: Max T. Buchko, Nasim Boroumand, Jeffrey C. Cheng, Alim Hirji, Kieran Halloran, Darren H. Freed, Jayan Nagendran
Format: Article
Language:English
Published: Nature Publishing Group 2020-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-19581-4