G-CSF Infusion for Stem Cell Mobilization Transiently Increases Serum Cell-Free DNA and Protease Concentrations

G-CSF Infusion for Stem Cell Mobilization Transiently Increases Serum Cell-Free DNA and Protease Concentrations

G-CSF for stem cell mobilization increases circulating levels of myeloid cells at different stages of maturation. Polymorphonuclear cells (PMNs) are also mobilized in high numbers. It was previously reported that G-CSF primes PMNs toward the release of neutrophils extracellular traps (NETs). Since N...

Full description

Bibliographic Details
Main Authors: Maria Stoikou, Shane V. van Breda, Günther Schäfer, Lenka Vokalova, Stavros Giaglis, Alexandra Plattner, Laura Infanti, Andreas Holbro, Sinuhe Hahn, Simona W. Rossi, Andreas Buser
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Medicine
Subjects:
G-CSF
stem cell mobilization
PMN
MPO
NE
ROS
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2020.00155/full

Internet

https://www.frontiersin.org/article/10.3389/fmed.2020.00155/full

Similar Items