Robust high-throughput assays to assess discrete steps in ubiquitination and related cascades

Robust high-throughput assays to assess discrete steps in ubiquitination and related cascades

Abstract Background Ubiquitination and ubiquitin-like protein post-translational modifications play an enormous number of roles in cellular processes. These modifications are constituted of multistep reaction cascades. Readily implementable and robust methods to evaluate each step of the overall pro...

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Bibliographic Details
Main Authors: Gabriel Fenteany, Paras Gaur, Gaurav Sharma, Lajos Pintér, Ernő Kiss, Lajos Haracska
Format: Article
Language:English
Published: BMC 2020-03-01
Series:BMC Molecular and Cell Biology
Subjects:
Ubiquitination
Ubiquitin-like proteins
Post-translational modifications
E1 ubiquitin-conjugating enzymes
E2 ubiquitin-conjugating enzymes
E3 ubiquitin ligases
Online Access:http://link.springer.com/article/10.1186/s12860-020-00262-5

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http://link.springer.com/article/10.1186/s12860-020-00262-5

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