MOLECULAR-GENETIC MARKERS OF RESPONSE TO NEOADJUVANT CHEMOTHERAPY WITH ANTHRACYCLINES IN BREAST CANCER PATIENTS

MOLECULAR-GENETIC MARKERS OF RESPONSE TO NEOADJUVANT CHEMOTHERAPY WITH ANTHRACYCLINES IN BREAST CANCER PATIENTS

The purpose of the study: to evaluate the response to neoadjuvant anthracycline-based chemotherapy depending on the presence of deletions and amplifications of different chromosomal loci and the expression level of topoisomerase 2а in tumor tissue of breast cancer patients. Materials and methods. Th...

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Bibliographic Details
Main Authors: P. V. Kazantseva, М. М. Tsyganov, Е. М. Slonimskaya, N. V. Litvyakov, Н. В. Cherdyntseva, М. K. Ibragimova, А. V. Doroshenko, N. А. Tarabanovskaya, S. V. Patalyak
Format: Article
Language:Russian
Published: Tomsk National Research Medical Center of the Russian Academy of Sciences 2016-07-01
Series:Sibirskij Onkologičeskij Žurnal
Subjects:
breast cancer
neoadjuvant chemotherapy
predictive markers
level of тор2а>5 expression
deletion of abc-transporter genes
dna copy number variations
Online Access:https://www.siboncoj.ru/jour/article/view/330

Internet

https://www.siboncoj.ru/jour/article/view/330

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