Novel GPR120 agonist TUG891 modulates fat taste perception and preference and activates tongue-brain-gut axis in mice

GPR120 is implicated as a lipid receptor in the oro-sensory detection of dietary fatty acids. However, the effects of GPR120 activation on dietary fat intake or obesity are not clearly understood. We investigated to determine whether the binding of TUG891, a novel GPR120 agonist, to lingual GPR120 m...

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Bibliographic Details
Main Authors: Babar Murtaza, Aziz Hichami, Amira S. Khan, Bharat Shimpukade, Trond Ulven, Mehmet Hakan Ozdener, Naim A. Khan
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520435321