State of Art of Idiosyncratic Drug-Induced Neutropenia or Agranulocytosis, with a Focus on Biotherapies

State of Art of Idiosyncratic Drug-Induced Neutropenia or Agranulocytosis, with a Focus on Biotherapies

Introduction: Idiosyncratic drug-induced neutropenia and agranulocytosis is seldom discussed in the literature, especially for new drugs such as biotherapies outside the context of oncology. In the present paper, we report and discuss the clinical data and management of this relatively rare disorder...

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Bibliographic Details
Main Authors: Emmanuel Andrès, Noel Lorenzo Villalba, Abrar-Ahmad Zulfiqar, Khalid Serraj, Rachel Mourot-Cottet, Jacques-Eric Gottenberg
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Journal of Clinical Medicine
Subjects:
drug
idiosyncratic
neutropenia
agranulocytosis
infections
antithyroid medications
ticlopidine
clozapine
sulfasalazine
antibiotics as trimethoprim-sulfamethoxazole (cotrimoxazole), and deferiprone
biotherapy
autoimmune disease
auto-inflammatory disorder
systemic vasculitis
orphan disease
anti-TNF-alpha agent
anti-CD20 agent
IL1-inhibitor
IL6 inhibitor
B-cell activating factor (BAFF) inhibitor
Online Access:https://www.mdpi.com/2077-0383/8/9/1351

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https://www.mdpi.com/2077-0383/8/9/1351

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